Lionheart Ventures is a seed-stage venture capital firm investing in transformative artificial intelligence and frontier mental health technologies to mitigate civilizational risk.
Lionheart Ventures is a seed-stage venture capital firm investing in transformative artificial intelligence and frontier mental health technologies to mitigate civilizational risk.
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Updated 06/25/26 · By grantmaking.aiFounder & Managing Partner
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Org Details
Updated 06/25/26 · By grantmaking.aiLionheart Ventures is a seed-stage venture capital firm headquartered in San Francisco, California, founded in 2019 by David Langer, a former entrepreneur who previously served as CEO of Zesty (acquired by Square) and GroupSpaces. The firm focuses on the wise development of transformative technologies, concentrating on two core sectors: artificial intelligence safety and frontier mental health technologies, including psychedelic medicine and neuromodulation.
In the AI sector, Lionheart invests in companies that defend and enhance human flourishing, agency, and resilience, with an explicit focus on ensuring the transition to powerful AI proceeds responsibly. Notable AI-focused investments include Anthropic and Softmax. In January 2024, the firm launched its Transformative AI Fund (Lionheart AI I), described as the first VC fund specifically focused on AI safety.
In mental health, Lionheart targets psychedelic-assisted therapies, novel pharmaceuticals, and non-invasive neurotechnologies. They view improvements in mental health as directly connected to political stability, democratic governance, and better collective decision-making. Portfolio companies in this space include Calm, Reconnect Labs, and others.
The firm has a core team of approximately 8 staff and partners, supported by a network of over 17 named advisors drawn from the AI safety and EA communities, including Jeffrey Ladish (Palisade Research), Richard Mallah (Future of Life Institute), Allison Duettmann (Foresight Institute), Justin Shovelain (Convergence Analysis), Zvi Mowshowitz, and Aaron Tucker (FAR AI). As of early 2023, the firm reported over $30 million in assets under management across its funds.
Theory of Impact
Updated 06/25/26 · By grantmaking.aiLionheart believes that venture capital can be a lever for reducing existential risk by directing capital toward companies that make AI development safer and more beneficial, and that improve humanity's collective wisdom and decision-making through mental health technologies. By investing in AI safety companies, they aim to ensure the AI transition proceeds with appropriate human oversight and alignment. By investing in mental health and consciousness technologies, they target an underappreciated pathway to existential risk reduction: improving societal decision-making capacity, political stability, and cooperative behavior. The firm also aims to bridge the EA and existential risk communities with the startup ecosystem, building norms and infrastructure for responsible transformative technology development.
Projects
Updated 06/25/26 · By grantmaking.aiDiscussion
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